Nebivolol Impurity 20 - Names and Identifiers
Nebivolol Impurity 20 - Physico-chemical Properties
Molecular Formula | C11H11FO2
|
Molar Mass | 194.2 |
Density | 1.299 |
Boling Point | 292℃ |
Flash Point | 138℃ |
Storage Condition | Room Temprature |
Nebivolol Impurity 20 - Risk and Safety
Nebivolol Impurity 20 - Introduction
(2R)-rel-6-Fluoro-3,4-dihydro-2-(2R)-, is also known as (2R)-rel-6-Fluoro-3,4-dihydro-2-(2R). The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow crystalline powder
-Molecular formula: C14H11FO2
-Molecular weight: 228.23g/mol
-Melting point: 95-98°C
-Boiling Point: 380-400°C
-Solubility: Soluble in organic solvents such as chloroform, ethanol and dimethylformamide
Use:
- (2R)-rel-6-Fluoro-3,4-dihydro-2-(2R)-is an important drug intermediate that can be used to synthesize a variety of drugs and biologically active compounds.
-It is commonly used in the field of medicine to synthesize antiviral drugs, anti-cancer drugs and anti-inflammatory drugs.
Preparation Method:
The preparation of (2R)-rel-6-Fluoro-3,4-dihydro-2-(2R)-is carried out by a synthetic route, and the specific steps are as follows:
1. a suitable compound is reacted with a fluorinating reagent through a chemical reaction to introduce a fluorine atom.
2. Under suitable conditions, the compound is subjected to an epoxidation reaction to form an oxirane group.
3. Further, the oxirane compound is reacted to make a ring nucleation reaction with benzopyran.
Safety Information:
(2R)-rel-6-Fluoro-3,4-dihydro-2-(2R)-and its safety information is limited, which may cause certain health and environmental risks to the human body. It should be handled and used in a suitable laboratory environment and in accordance with the relevant safety procedures. For the specific safety assessment and use restrictions of this compound, refer to the relevant chemical safety data sheets and technical literature, and follow the correct use and handling methods.
Last Update:2024-04-09 02:00:48